Add to ORKG"Scientists Against Malaria" (SAM) is an international virtual organization designed to apply modern drug design and modeling techniques in combination with industry std. infrastructure and interdisciplinary science to develop new treatments against malaria. Our strategy strongly relies on the use and development of a novel collaborative research workflow where several computational and exptl. groups meet thanks to new technol. information systems.[p]The first pipeline project of SAM will be described, which is devoted to finding hit compds. against the genetically validated target Pfmap-2 (a P. Falciparum MAP kinase) from a novel chem. library. The strategy involves several virtual screening techniques, including pharmacophore based sea...
<div><p>A major cause of the paucity of new starting points for drug discovery is the lack of intera...
A major cause of the paucity of new starting points for drug discovery is the lack of interaction be...
Malaria caused by Plasmodium falciparum is a disease that is responsible for 880,000 deaths per year...
Herein is reported the authors\u2019 experiences in establishing the Scientists Against Malaria (SAM...
The over growing burden of antimalarial drug resistance places much emphasis on the immediate develo...
Background: Despite continuous efforts of the international community to reduce the impact of malari...
The Open Source Malaria (OSM) consortium is developing compounds that kill the human malaria parasit...
Background: The critically important issue on emergence of drug-resistant malarial parasites is comp...
The Open Source Malaria (OSM) consortium is developing compounds that kill the human malaria parasit...
We describe the application of ligand based virtual screening technologies towards the discovery of ...
The drive to propagate a species genes is among the strongest biological forces, shared by humans an...
The growing resistance to current first-line antimalarial drugs represents a major health challenge....
Malaria causes about half a million deaths annually, with Plasmodium falciparum being responsible fo...
Compared to the previous year, there has been an increase of nearly 2 million malaria cases in 2021....
The main challenge in the control of malaria has been the emergence of drug-resistant parasites. The...
<div><p>A major cause of the paucity of new starting points for drug discovery is the lack of intera...
A major cause of the paucity of new starting points for drug discovery is the lack of interaction be...
Malaria caused by Plasmodium falciparum is a disease that is responsible for 880,000 deaths per year...
Herein is reported the authors\u2019 experiences in establishing the Scientists Against Malaria (SAM...
The over growing burden of antimalarial drug resistance places much emphasis on the immediate develo...
Background: Despite continuous efforts of the international community to reduce the impact of malari...
The Open Source Malaria (OSM) consortium is developing compounds that kill the human malaria parasit...
Background: The critically important issue on emergence of drug-resistant malarial parasites is comp...
The Open Source Malaria (OSM) consortium is developing compounds that kill the human malaria parasit...
We describe the application of ligand based virtual screening technologies towards the discovery of ...
The drive to propagate a species genes is among the strongest biological forces, shared by humans an...
The growing resistance to current first-line antimalarial drugs represents a major health challenge....
Malaria causes about half a million deaths annually, with Plasmodium falciparum being responsible fo...
Compared to the previous year, there has been an increase of nearly 2 million malaria cases in 2021....
The main challenge in the control of malaria has been the emergence of drug-resistant parasites. The...
<div><p>A major cause of the paucity of new starting points for drug discovery is the lack of intera...
A major cause of the paucity of new starting points for drug discovery is the lack of interaction be...
Malaria caused by Plasmodium falciparum is a disease that is responsible for 880,000 deaths per year...